Term Stim™

Term Stimulation (Term Stim™) is an approach to ovarian stimulation that extends the follicular phase to the duration seen in the most fertile group of females – about 17 days. This is achieved by maintaining the level of FSH in blood within the narrow band optimized for the specific patient.  We were able to demonstrate that it improves egg quality in younger as well as in patients of advanced reproductive age.  

Egg quality in IVF is the single most important variable predicting the success of the treatment.

Just like a pregnancy has to be – term to deliver a competent newborn, a term ovarian stimulation is intended to deliver competent egg. 

Term Stim™ (a short for Term Stimulation) came to existence as a derivative of a see changes in reproductive physiology pioneered by Dr. Dmitri Dozortsev, Dr. Michael P. Diamond and Dr. Antonio Pellicer

Term Stim™ is not a mere extension of the duration of stimulation, but is based on a complex algorithm that maintains the level of FSH within a narrow band. 

Term Stim helps those women who previously failed IVF multiple times due to poor egg quality, including those who are older. Term Stim™ requires more attention to detail and is more time-consuming than conventional ovarian stimulation. Therefore, at this time it has largely been used for patients who had two prior cycles of IVF with poor embryo quality, attributed to poor egg quality. 

 

Convention stimulation relies on the level of E2 and follicle size to determine whether the response is adequate. Term Stim monitors the level of FSH to ensure that it remains within the safe range to achieve the desirable duration of artificial follicular phase (time).  

Example

Term Stim™ provides more data points to help physicians have a deeper insight into what is happening.